Everything you need to know about Secretome Complex — from science and safety to ordering and storage.
Secretome Complex is a cell-free mixture of biologically active substances released by cultured umbilical cord–derived mesenchymal stromal cells (UC-MSCs). It contains growth factors, cytokines, chemokines, natural peptides, proteins, enzymes, lipids and extracellular vesicles — but no living stem cells. "Complex" means it is a natural combination of secreted components rather than a single purified ingredient.
No. The final product is completely cell-free. During manufacturing, the conditioned medium is collected from cultured UC-MSCs, then filtered and concentrated. No viable cells remain in the finished vial. This eliminates the risks associated with handling living cells and gives the product different storage characteristics from live UC-MSCs.
The KingStemCell UC-MSC secretome contains high levels of Angiopoietin-2, HGF (Hepatocyte Growth Factor), M-CSF, SCF, PDGF-BB, PDGF-AA, VEGF, FGF-basic and other bioactive molecules. The exact concentrations are validated batch to batch under GMP conditions.
Yes. KingStemCell's manufacturing process is fully defined, FBS serum-free, xeno-free (no animal-derived components) and DMSO-free. This ensures the highest purity and consistency for cosmetic and wellness applications.
Secretome Complex is intended for licensed healthcare practitioners, aesthetic clinics, medical spas and qualified cosmetic formulators. If you need practitioner access or bulk pricing, please contact us through our contact form.
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Because the product is cell-free, it has different storage requirements from live UC-MSCs. Store according to the product label and Certificate of Analysis provided with each batch. Contact us for detailed storage and handling guidelines for your specific application.
Yes. Secretome Complex can be incorporated into serums, creams, microneedle patches, transdermal delivery systems and other topical formulations while maintaining formulation stability. It serves as a strong biological foundation for next-generation cosmetic product platforms.
Umbilical cord–derived MSCs have a neonatal origin and high metabolic activity, which may provide enhanced regenerative potential compared to adult-derived sources like bone marrow or adipose tissue. Under GMP conditions, UC-MSC secretomes also deliver a more consistent and reproducible molecular profile.
Secretome Complex is a cell-free biologic intended for use by licensed healthcare practitioners and qualified formulators in cosmetic and wellness applications. Statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Our team is here to help with product information, practitioner access and formulation guidance.